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The Effect of Humic Acid Substances on the Thyroid Function and Structure in Lead Poisoning Rev. Bras. Ciênc. Avic.
Sahin,A; Iskender,H; Terim,Kapakin KA; Altinkaynak,K; Hayirli,A; Gonultas,A; Kaynar,O.
ABSTRACT Lead (Pb) is a heavy metal, which adversely affects thyroid gland function and structure. Due to its high molecular weight and abundant functional groups, humic acid substances (HAS) can form chelates with heavy metals. The experiment was conducted to evaluate the prophylactic effect of HAS on thyroid hormone levels and histopathological lesions of laying hens exposed to lead (Pb) poisoning. After a week of adaptation, 192 Lohmann White laying hens (25 weeks of age) were fed one of four diets: a basal diet (BD) or the BD with HAS (0.15%), with Pb (0.3 g/kg), or with both. Experimental groups were replicated in 12 cages, with four hens each. Pb poisoning did not alter triiodothyronine (FT3; 3.22 ± 0.20 ng/dL) or thyroxine (FT4; 0.71 ± 0.08 ng/dL)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lead poisoning; Humic acid substances; Thyroid gland; Chicken.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2016000400649
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